SAF-2, a Splice Variant of SAF-1, Acts as a Negative Regulator of Transcription
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چکیده
منابع مشابه
Inflammation-responsive transcription factor SAF-1 activity is linked to the development of amyloid A amyloidosis.
Abundantly expressed serum amyloid A (SAA) protein under chronic inflammatory conditions gives rise to insoluble aggregates of SAA derivatives in multiple organs resulting in reactive amyloid A (AA) amyloidosis, a consequence of rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, familial Mediterranean fever, and Castleman's disease. An inflammation-responsive transcription factor, S...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m206299200